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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
33.64
Human Site:
T412
Identified Species:
52.86
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
T412
N
Q
V
F
L
G
F
T
Y
V
A
P
S
V
L
Chimpanzee
Pan troglodytes
XP_523815
451
50966
G341
S
R
L
G
A
G
P
G
D
A
G
E
V
Q
A
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
T412
N
Q
V
F
L
G
F
T
Y
V
A
P
S
V
L
Dog
Lupus familis
XP_537702
525
59107
T412
N
Q
V
F
L
G
F
T
Y
V
A
P
S
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
T412
N
Q
V
F
L
G
F
T
Y
V
A
P
S
V
L
Rat
Rattus norvegicus
P67999
525
59113
T412
N
Q
V
F
L
G
F
T
Y
V
A
P
S
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
T369
N
Q
V
F
L
G
F
T
Y
V
A
P
S
V
L
Chicken
Gallus gallus
P18652
752
84421
F399
Q
L
F
R
G
F
S
F
V
A
T
G
L
M
E
Frog
Xenopus laevis
P10666
629
71268
S380
H
Q
L
F
R
G
F
S
F
V
A
P
V
L
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
N402
S
K
S
A
P
L
V
N
I
L
P
I
V
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
L1065
Y
E
D
S
K
A
S
L
R
V
L
M
Q
Q
L
Honey Bee
Apis mellifera
XP_395876
456
51514
P345
V
I
S
R
K
L
E
P
P
F
R
P
T
L
A
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
S422
H
E
I
F
R
G
F
S
F
V
S
N
A
V
M
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
S375
T
K
Q
T
P
V
D
S
P
D
D
S
M
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
S360
I
K
L
P
Q
F
L
S
N
E
A
H
A
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
0
46.6
0
N.A.
13.3
6.6
33.3
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
6.6
86.6
26.6
N.A.
20
20
86.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
7
0
0
0
14
54
0
14
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
0
7
7
7
0
0
0
0
% D
% Glu:
0
14
0
0
0
0
7
0
0
7
0
7
0
0
7
% E
% Phe:
0
0
7
54
0
14
54
7
14
7
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
60
0
7
0
0
7
7
0
0
0
% G
% His:
14
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
7
7
7
0
0
0
0
0
7
0
0
7
0
0
0
% I
% Lys:
0
20
0
0
14
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
7
20
0
40
14
7
7
0
7
7
0
7
27
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
7
% M
% Asn:
40
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
7
14
0
7
7
14
0
7
54
0
0
0
% P
% Gln:
7
47
7
0
7
0
0
0
0
0
0
0
7
20
0
% Q
% Arg:
0
7
0
14
14
0
0
0
7
0
7
0
0
0
0
% R
% Ser:
14
0
14
7
0
0
14
27
0
0
7
7
40
0
7
% S
% Thr:
7
0
0
7
0
0
0
40
0
0
7
0
7
0
0
% T
% Val:
7
0
40
0
0
7
7
0
7
60
0
0
20
47
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _